Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Determination of the Effects of Material from Alternate Energy Sources on the Upper Respiratory Tract Clearance Mechanism. Part I: In vitro Exposure to Particulate Pollutants. Part II: In vivo Exposure to Ozone.
Author Adalis, Dorothy ;
CORP Author Ball State Univ., Muncie, IN.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-68-02-2295; EPA/600/1-81-067;
Stock Number PB82-117037
Additional Subjects Toxicology ; Respiratory system ; Clearances ; In vitro analysis ; Hamsters ; Laboratory animals ; Ozone ; Nickel ; Vanadium ; Zinc ; Exposure ; Physiological effects ; Pathology ; Cilia ; Trachea ; Tissue cultures ; Toxic substances ; Animal models ; Particulates ; Air pollution effects(Animals) ; Heavy metals
Library Call Number Additional Info Location Last
NTIS  PB82-117037 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 75p
Studies were conducted to measure the toxic effects of a variety of substances from the environment on the clearance mechanism of the upper respiratory tract using an in vitro hamster model system. Studies using hamsters for in vivo exposures to ozone were also conducted to determine the effects of ozone on the cilia beat frequency and cytopathology of the tracheal epithelium. Organ cultures of hamster tracheal tissue were exposed to graded concentrations of pollutants to determine effects on the respiratory cilia. Parameters studied were beat frequency, ciliostasis, cytopathology, and ATP concentration.