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RECORD NUMBER: 585 OF 1202

Main Title Intestinal Cu Absorption in Vitro After Fe or Zn Depletion (Intestinale Cu-Absorption in vitro nach Feoder Zn-Depletion).
Author Schwarz, F. J. ; Kirchgessner., M. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1973
Report Number EPA-TR-74-374;
Stock Number PB-252 814-T
Additional Subjects Copper ; Absorption(Biology) ; Trace elements ; Metals ; Depletion ; Iron ; Zinc ; Intestines ; Physiology ; In vitro analysis ; Rats ; Experimental data ; Translations ; West Germany ;
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NTIS  PB-252 814-T Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 17p
Abstract
Cu absorption after Fe or Zn depletion was measured in vitro with everted sacs of rats. The experimental animals were depleted with a casein diet low in Fe or in Zn. The Cu transfer to the serosa solution of anemic intestines remained unchanged compared with that of Fe-supplied intestinal segments; only after Cu depletion the Cu transfer was 50-80% higher. In Zn deficiency the Cu transfer to the serosa solution, as well as the Cu uptake by the intestinal wall, was clearly elevated (P < 0.001). Since after Zn depletion the Zn absorption was elevated about threefold, possible interactions between zinc and copper in the uptake and transfer of these trace elements are discussed.