Record Display for the EPA National Library Catalog


Main Title In vitro toxicity testing of environmental agents : current and future possibilities /
Author Kolber, Alan R.
Other Authors
Author Title of a Work
Kolber, Alan R.
CORP Author North Atlantic Treaty Organization. Scientific Affairs Division.
Publisher Plenum Press,
Year Published 1983
OCLC Number 08764657
ISBN 0306411237; 9780306411236; 0306411245; 9780306411243
Subjects Environmental health--Evaluation--Congresses ; Toxicity testing--In vitro--Congresses ; Environmental Pollutants--toxicity ; Toxicology--methods ; Analise toxicologica
Additional Subjects Environmental health--Evaluation--Congresses ; Toxicity testing--Congresses
Library Call Number Additional Info Location Last
EKBM  RA565.A2N37 1979 Research Triangle Park Library/RTP, NC 01/01/1988
EKCM  RA565.A2N37 1979 pt.A-B CEMM/GEMMD Library/Gulf Breeze,FL 11/17/2015
ELBM  RA565.A2N37 1979 v.5A-B AWBERC Library/Cincinnati,OH 09/10/1988
Collation 2 volumes : illustrations, charts, photographs ; 26 cm.
Includes bibliographical references and index. "Proceedings of a NATO Advanced Research Institute on 'In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities, ' held September 22-28, 1979, in Monte Carlo, Monaco"--Title page verso. Published in cooperation with NATO Scientific Affairs Division
Contents Notes
pt. A. Survey of test systems -- pt. B. Development of risk assessment guidelines. These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car cinogenesis, mutagenesis, and transformation; (3) bacterial muta genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.