The paper presents the results of screening for 25 different adsorbents and indicates which were most suitable for further study. The list includes a number of readily available pharmaceutical or household materials as well as a few adsorbent materials commonly found in chemistry laboratories. The results of this study indicate that, of the materials tried, Amberlite CG-120, either 100-200 or 200-400 mesh, is the most promising adsorbent for study on experimental animals. A limited amount of exploratory animal work at this laboratory has shown the Amberlite resins to be effective in reducing tissue levels compared with nonprotected animals and, in some cases, there was indication of protection against poisoning.