Record Display for the EPA National Library Catalog

RECORD NUMBER: 413 OF 821

Main Title Methodology for estimating direct exposure to new chemical substances /
Author Becker, David. ; Fochtman, Edward ; Gray, Allan ; Jacobius, Thomas
Other Authors
Author Title of a Work
Kamely, Daphne.
McSorley, Joseph.
CORP Author IIT Research Inst., Chicago, IL.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher U.S. Environmental Protection Agency, Office of Toxic Substances,
Year Published 1979
Report Number EPA-560/13-79-008; 68-02-2617; IITRI-C6390-C08; EPA-68-02-2617
Stock Number PB80-102262
OCLC Number 27096907
Subjects Chemicals--Physiological effect ; Chemical industry--Safety measures ; Risk assessment
Additional Subjects Methodology ; Estimating ; Exposure ; Predictions ; Humans ; Physical properties ; Chemical properties ; Industrial medicine ; Consumers ; Assessments ; Risk ; Toxic substances ; Toxic Substances Control Act ; Public Law 94-469 ; Occupational safety and health
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=91013G6A.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJED  EPA 560-13-79-008 OCSPP Chemical Library/Washington,DC 04/22/2012
ELBD ARCHIVE EPA 560-13-79-008 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
NTIS  PB80-102262 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation vii, [131] p. ; 28 cm.
Abstract
The Toxic Substances Control Act (TSCA) requires each person who intends to manufacture a new chemical to submit a Premanufacturing Notice to the EPA at least 90 days before manufacture commences. The work reported was directed toward the development of a procedure for the orderly and rapid prediction of direct human exposure which might result from such manufacture. The procedure developed involves the following steps: (1) prediction of unavailable physical and chemical properties from analogs and general chemical knowledge, (2) prediction of production volume based upon company size, current markets and total market volume, (3) prediction of chemical operator exposure and exposures in the vicinity of the plant based upon fugitive emissions and (4) prediction of consumer exposure based upon active use and passive use of the chemical. The procedure will permit rapid screening however further refinements will enhance the usefulness.
Notes
Includes bibliographical references. "July, 1979." "EPA-560/13-79-008." "IIT Research Institute ... Contract no. 68-02-2617, task no. 8; project officer: Daphne Kamely; program manager: Joseph McSorley."