This report is divided into seven sections. Section I briefly describes the Chesapeake Bay Water Quality Model and introduces the scenarios analyzed. Section II describes the scenarios and associated nutrient sediment loads in detail. The third section provides background for the more detailed analysis of Bay water quality response that follows. Sections IV and V summarize aspects of Bay circulation and its influence on water quality. Section VI surveys the nutrient, phytoplankton, and sediment response to loading reductions. Section VI also examines the overall nutrient budget and the exchange among the tributaries and mainstem. Section VII concludes the report with a detailed examination of the mainstem dissolved oxygen response to the interactions among nutrient loads, transport, sediment processes, and phytoplankton processes examined in the previous sections. A summary of major findings is included in each section and an overview of these findings is provided in the Technical Summary.