| Main Title |
Molecular Topology and Narcosis - A Quantitative Structure-Activity Relationship (QSAR) Study of Alcohols Using Complementary Information Content (CIC). |
| Author |
Basak, S. C. ;
Magnuson, V. R. ;
|
| CORP Author |
Minnesota Univ.-Duluth.;Environmental Research Lab.-Duluth, MN. |
| Year Published |
1983 |
| Report Number |
EPA-R-807566; EPA-600/J-83-072; |
| Stock Number |
PB84-110055 |
| Additional Subjects |
Molecular structure ;
Alcohols ;
Drugs ;
Topology ;
Narcosis ;
Reprints ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-110055 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
A newly formulated information -theoretic topological index - complementary information content (CIC) - defined for the planar chemical graph of molecules is applied in the QSAR studies of congeneric series of alcohols. Results show that CIC can quantitatively predict the LC50 values of the congeners at a level comparable with that of log P. |
