Record Display for the EPA National Library Catalog

RECORD NUMBER: 2 OF 13

Main Title Health assessment document for toluene /
Author Basu, Dipak ; Bosch, Stephen ; Colman, Joan ; Durkin, Patrick ; Foote, Knowlton
Other Authors
Author Title of a Work
Greenberg, Mark M.
CORP Author Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.;Environmental Protection Agency, Research Triangle Park, NC. Environmental Criteria and Assessment Office.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Criteria and Assessment Office,
Year Published 1982
Report Number EPA-600/8-82-008; EPA-68-02-3277; 600D82380
Stock Number PB83-136002
OCLC Number 20699141
Subjects Toluene--toxicity. ; Toluene--adverse effects. ; Environmental Pollutants.
Additional Subjects Toluene ; Toxicology ; Industrial medicine ; Aromatic hydrocarbons ; Exposure ; Humans ; Central nervous system ; Rats ; Bioassay ; Air pollution ; Physical properties ; Chemical properties ; Risk ; Air pollution effects(Humans) ; Threshold limit values ; Toxic substances ; Occupational safety and health ; Analytical methods ; Pharmacokinetics ; Health risks
Internet Access
Description Access URL
Part 2 https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100C6SS.PDF
Part 1 https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100RRQ4.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJED  EPA 600-8-82-008 OCSPP Chemical Library/Washington,DC 01/13/2001
ESAD  EPA 600-8-82-008 2 vols. Region 10 Library/Seattle,WA 04/11/2017
NTIS  PB83-136002 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 2 pts. (various pagings) : ill.
Abstract
The health effect of primary concern with regard to exposures of humans to toluene is dysfunction of the central nervous system (CNS). Occupational exposures in the range of 200 to 1,500 ppm have elicited dose-related CNS alterations. Although myelotoxicity was previously attributed to toluene, recent evidence indicated that toluene is not toxic to the blood or bone marrow; myelotoxic effects are considered to have been the result of concurrent exposure to benzene. Available evidence is inadequate for assessing the carcinogenic potential of toluene. Although a 24-month inhalation exposure of rats to 300 ppm did not produce any positive carcinogenic effects, various design deficiencies precluded the usefulness of this study in assessing carcinogenic potential.
Notes
"Review Draft." "EPA-600/8-82-008" (cover). "March 1982" (cover). Includes bibliography.