Record Display for the EPA National Library CatalogRECORD NUMBER: 2 OF 5
|Main Title||Evaluation of the potential carcinogenicity of 3,3'-dimethylbenzidine (119-93-71) /|
|CORP Author||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA/600/8-91/118; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-093|
|Subjects||Tolidine--Carcinogenicity ; Dimethylbenzidine--Carcinogenicity|
|Additional Subjects||Carcinogens ; Toxicity ; Humans ; Animals ; Carcinogenicity tests ; Dose-response relationships ; Risk assessment ; Dimethylbenzidines ; CAS 119-93-7|
|Collation||18 pages ; 28 cm|
3,3'-Dimethylbenzidine is a possible human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is No Data. The potency factor (F) for 3,3'-dimethylbenzidine is estimated to be 27.4 (mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, 3,3'-dimethylbenzidine is assigned a MEDIUM hazard ranking for the purposes of RQ adjustment.
Cover title. "June 1988." Includes bibliographical references. Microfiche.