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RECORD NUMBER: 41 OF 96

OLS Field Name OLS Field Data
Main Title Initial Submission: TSCA Health and Safety Study Cover Sheet Reporting Preliminary Results from Developmental Toxicity Screening in Rats after Oral Administration of and 7370, dated 08/16/1999.
CORP Author Bayer A.G., Dormagen (Germany, F.R.).; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Report Number 8EHQ-0899-14532
Stock Number OTS0559779
Additional Subjects Toxicology ; Oral administration ; Rats ; Toxicity ; Dosage ; Females ; Pregnancy ; Gavage ; Fetuses ; Tolerance ; Weight ; Mortality ; Evaluation ; Laboratory animals ; Toxic substances ; AND 7370 ; Experimental herbicide ; CAS No 99-2-58
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Status
NTIS  OTS0559779 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 04/28/2010
Collation 6p
Abstract
Four inseminated Wistar rats (two rats in the 100 mg/kg dose group had implantation sites; i.e., were pregnant) were treated daily from day 6 to day 19 p.c. by gavage, with 100 or 1000 mg/kg body weight/day of AND 7370 in 0.5% carboxymethylcellulose in demineralized water. The fetuses were delivered by cesarean section on day 20 p.c. Investigations were performed on the general tolerance of the test compound by the females as well as on its effects on intrauterine development (pregnancy rate, number of fetuses and resorptions, external findings in the fetuses, fetal weight, fetal skeletal malformations, and fetal skeletal variations (wavy ribs only)).