| Main Title |
Toxicological review of tetrahydrofuran (CAS No. 109-99-9) : in support of summary information on the Integrated Risk Information System (IRIS) / |
| Other Authors |
|
| CORP Author |
Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment. |
| Publisher |
U.S. Environmental Protection Agency, |
| Year Published |
2012 |
| Report Number |
EPA/635/R-11/006F |
| Stock Number |
PB2012-108148 |
| OCLC Number |
779978088 |
| Subjects |
Tetrahydrofuran--Toxicology
|
| Additional Subjects |
Toxicity ;
Tetrahydrofuran ;
Health hazards ;
Dose response relationships ;
Cancer ;
Environmental exposure ;
Chemical properties ;
Risk assessment ;
Integrated Risk Information System(IRIS) ;
CAS No 109-99-9
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJAI |
via Internet only |
|
Region 3 Library/Philadelphia, PA |
05/30/2012 |
| NTIS |
PB2012-108148 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
[207] pages : illustrations, color graphs ; digital, PDF file |
| Abstract |
The purpose of this toxicological review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to tetrahydrofuran. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of tetrahydrofuran. The intent of Section 6, Major Conclusions in the Characterization of Hazard and Dose Response, is to present the major conclusions reached in the derivation of the reference dose, reference concentration and cancer assessment, where applicable, and to characterize the overall confidence in the quantitative and qualitative aspects of hazard and dose response by addressing the quality of data and related uncertainties. The discussion is intended to convey the limitations of the assessment and to aid and guide the risk assessor in the ensuing steps of the risk assessment process. |
| Notes |
Title from PDF title screen (viewed 3/13/2012). Includes bibliographical references. "February 2012." "EPA/635/R-11/006F." |
| Contents Notes |
"This document presents background information and justification for the Integrated Risk Information System (IRIS) Summmary of the hazard and dose-response assessment of tetrahydrofuran (THF). IRIS Summaries may include oral reference dose (RfD) and inhalation reference concetration (RfC) values for chronic and other exposure durations, and a carcinogenicity assessment." p. 15. |
