||Concentration of DDT in Brain and Other Tissues in Relation to Symptomatology.
Haven, Jr., Wayland J. ;
Dale., William E. ;
||National Communicable Disease Center, Atlanta, Ga.
Signs and symptoms ;
Toxic substances ;
Pesticide residues ;
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Following repeated doses of DDT at a dietary rate of 200 ppm, rats tolerated without significant inconvenience storage of the compound in the lipids of adipose tissue in concentrations averaging > 500 ppm in males and > 1400 in females. Under these conditions, the concentration of DDT in the brain lipids did not exceed 280 ppm and averaged < 170 ppm. Animals that died following repeated doses showed concentrations of DDT in brain lipid ranging from 205 to 985 and averaging 595 ppm in males and 767 ppm in females.