Record Display for the EPA National Library Catalog


Main Title Comprehensive progress report for Fourier transform NMR of metals of environmental significance /
Author Ellis, Paul D.
Other Authors
Author Title of a Work
Odom, Jerome D.
CORP Author South Carolina Univ., Columbia. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1979
Report Number EPA 600/1-79/035; EPA-R-804359
Stock Number PB80-137490
OCLC Number 42926089
Subjects Nuclear magnetic resonance spectroscopy--Research. ; Metals--Analysis. ; Cadmium--Isotopes--Spectra.
Additional Subjects Nuclear magnetic resonance ; Selenium ; Cadmium ; Environmental surveys ; Biochemistry ; Amino acids ; Proteins ; Molecular relaxation ; Toxicology ; Public health ; Probes ; Pollution ; Fourier transform spectroscopy ; Chemical shifts(Nuclear magnetic resonance) ; Heavy metals ; Concanavalin A ; Superoxide dismutase ; Peptidase/carboxy ; Cadmium 113 ; Selenium 77
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-79-035 Headquarters Library/Washington,DC 01/30/2012
EJBD  EPA 600-1-79-035 Headquarters Library/Washington,DC 04/25/2014
EKBD  EPA-600/1-79-035 Research Triangle Park Library/RTP, NC 06/30/2000
NTIS  PB80-137490 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation x, 81 pages : figures ; 28 cm.
Interactions of the metals cadmium and selenium with various biologically important substrates were studied by nuclear magnetic resonance (NMR) spectroscopy. Cadmium-113 NMR was used for a critical examination of three metalloproteins: concanavalin A, bovine superoxide dismutase and carboxypeptidase A. The NMR parameters of selenium-77 were investigated, with a view to using this nucleus as a probe of active site sulfydryl groups in proteins. Several advances in NMR instrumentation were developed to further the aims of this project. One is a unique NMR probe, capable of spinning large (18 mm) NMR tubes, decoupling at any frequency, and observing any NMR-active nuclei. A decoupler modification, 'Chirp' decoupling, was developed. This modification allows good experimental results with approximately 1/10 the power required without modification.
"EPA-600/1-79/035." EPA grant no. R804359 ; EPA project officer: Nancy K. Wilson. Includes bibliographical references (pages 53-61).