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RECORD NUMBER: 40 OF 379

Main Title Assessment of the Oral Toxicity, Including the Haemolytic Activity of Dowanol-pnb in the Rat: 14-day Study with Attachments.
CORP Author Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001253
Stock Number OTS0520763
Additional Subjects Toxicology ; Health effects ; Propylene Glycol-n-butyl Ether (5131-66-8) ; Subchronic Toxicity ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 5131-66-8
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NTIS  OTS0520763 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 83p
Abstract
Propasol B (CAS No. 5131-66-8) was evaluated for subchronic toxicity. The test substance was administered by gavage to rats (6/sex/group) at doses of 0, 100, 200, and 400 mg/kg body weight for 14 consecutive days. No mortalities or obvious signs of systemic toxicity were observed. Treated rats did not differ from controls in body weight gain, food consumption, organ weights, organ/body weights, clinical chemistry, hematology, or gross and microscopic pathology of liver, adrenals, kidneys, spleen, heart, testes, and ovaries.