Record Display for the EPA National Library Catalog

RECORD NUMBER: 297 OF 379

Main Title Subchronic Inhalation Toxicity of Hexafluoropropylene with Cover Letter.
CORP Author Du Pont de Nemours (E.I.) and Co., Wilmington, DE.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1985
Report Number 878215099
Stock Number OTS0206763
Additional Subjects Toxicology ; Health effects ; Fluoroalkenes ; Subchronic Toxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 116-15-4
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS0206763 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 75p
Abstract
Subchronic inhalation toxicity was evaluated in groups of 10 male Crl:CD(SD)BR rats exposed to atmospheres containing hexafluoropropylene at mean concentrations (analyzed by gas chromatography) of 0, 10, 50 or 200 ppm for 6 h/d, 5 d/week for 2 weeks. There were no mortalities reported. Clinical observations included no compound-related signs of toxicity. There were no treatment-related hematological or clinical chemical effects observed. Necropsy revealed no compound-related changes in organ weights, however mild nephrosis in the kidneys was observed in high- dose rats. This was absent after 14 days recovery.