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Main Title Molecular aspects of the stress response : chaperones, membranes and networks /
Other Authors
Author Title of a Work
Csermely, Peter.
Vâigh, Lâaszlâo,
Publisher Springer Science+Business Media, LLC ; Landes Bioscience/,
Year Published 2007
OCLC Number 77496248
ISBN 9780387399744; 0387399747
Subjects Stress (Physiology) ; Molecular chaperones ; Protein folding ; Heat shock proteins ; Stress, Physiological ; Cell Physiological Phenomena ; Moleculaire biologie
Internet Access
Description Access URL
Publisher description
Library Call Number Additional Info Location Last
ELBM  QP82.2.S8M62 2007 AWBERC Library/Cincinnati,OH 12/07/2015
Collation xviii, 201 pages : illustrations, portraits.
Includes bibliographical references and index.
Contents Notes
Protein misassembly: macromolecular crowding and molecular chaperones / R. John Ellis -- The cellular "networking" of mammalian HSP27 and its functions in the control of protein folding, redox state and apoptosis / André-Patrick Arrigo -- Molecular interaction network of the HSP90 chaperone system / Rongmin Zhao and Walid A. Houry -- Organization of the functions and components of the endoplasmic reticulum / Yuichiro Shimizu and Linda M. Hendershot -- Molecular crime and cellular punishment: active detoxification of misfolded and aggregated proteins in the cell by the chaperone and protease networks / Marie-Pierre Hinault and Pierre Goloubinoff -- Chaperones as parts of cellular networks / Peter Csermely, Csaba Sèoti and Gregory L. Blatch -- Chaperones as parts of organelle networks / Gyèorgy Szabadkai and Rosario Rizzuto -- Heat shock factor 1 as a coordinator of stress and developmental pathways / Julius Anckar and Lea Sistonen -- Chaperone regulation of the heat shock protein response / Richard Voellmy and Frank Boellmann -- Mechanisms of activation and regulation of the heat shock-sensitive signaling pathways / Sébastien Ian Nadeau and Jacques Landry -- Membrane-regulated stress response: a theoretical and practical approach / László Vígh [and others] -- Beyond the lipid hypothesis: mechanisms underlying phenotypic plasticity in inducible cold tolerance / Scott A.L. Hayward [and others] -- Trehalose as a "chemical chaperone:" fact and fantasy / John H. Crowe -- Chaperones as part of immune networks / Zoltán Prohászka -- The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging / Heather R. Brignull, James F. Morley and Richard I. Morimoto -- HSP90 and developmental networks / Suzannah Rutherford, Jennifer R. Knapp and Peter Csermely. This book is authored by an exciting mixture of top experts and young rising stars from the fields of molecular chaperones and stress adaptation. In addition to giving a comprehensive summary with original references to their field, all authors share their hypotheses and vision on future trends with the reader. The book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. A novel perspective of "old facts" is provided in each chapter, where "old" means only 5-10 years in this rapidly expanding field.