Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Methods for Assessing Rat Sperm Motility.
Author Chapin, R. E. ; Filler, R. S. ; Gulati, D. ; Heindel, J. J. ; Katz, D. F. ;
CORP Author National Toxicology Program, Research Triangle Park, NC. ;American Cyanamid Co., Pearl River, NY. Lederle Labs. Div. ;Environmental Health Research and Testing, Inc., Lexington, KY. ;California Univ., Davis. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1992
Year Published 1992
Report Number EPA-68-02-4450; EPA/600/J-92/229;
Stock Number PB92-195825
Additional Subjects Sperm motility ; Rats ; Tests ; Microcomputers ; Interlaboratory comparisons ; Epididymis ; Toxicology ; Reprints ; Computer-assisted sperm analysis
Library Call Number Additional Info Location Last
NTIS  PB92-195825 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 08/22/1992
Collation 9p
Computer-assisted sperm analysis (CASA) systems are becoming more widely used. With this spread of technology come more data from toxicology studies, designed to determine if treatment with putative toxicants affects sperm motion parameters. While these CASA methods provide us with more ways to evaluate toxicity, and thus perhaps increase the chances of successfully protecting human health, there is also a greater likelihood that different laboratories will use different methods of collecting data on sperm motility. Different systems and different methods will produce data that are difficult to compare. In a prospective attempt to address this issue of comparability and limit the problems, a group of individuals using CASA systems to analyze rat sperm motility convened to discuss methodologic issues, share data, and tried to reach a consensus about methods for performing these studies. The manuscript shares those meetings and data in the hope that common methods will enhance inter-laboratory comparisons. (Copyright (c) 1992 Pergamon Press Ltd.)