Record Display for the EPA National Library Catalog

RECORD NUMBER: 40 OF 87

Main Title Health Assessment for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. Chapter 1. Disposition and Pharmacokinetics.
Author Olson, J. ;
CORP Author Syracuse Research Corp., NY.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher Aug 92
Year Published 1992
Report Number EPA-68-C0-0043; EPA/600/AP-92/001A ; OHEA-I-486-VOL-1
Stock Number PB93-222651
Additional Subjects Tetrachlorodibenzodioxin ; Dioxins ; Pharmacokinetics ; Toxicity ; Public health ; Risk assessment ; Species specificity ; Exposure ; Biological availability ; Absorption(Biology) ; Metabolism ; Excretion ; Dose-response relationships
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=30006C3P.PDF
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=200131WQ.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-222651 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 134p
Abstract
The U.S. Environmental Protection Agency (EPA) is conducting a scientific reassessment of the risks of exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and chemically similar compounds collectively known as dioxin. The disposition and pharmacokinetics of TCDD and related compounds have been investigated in several species and under various exposure conditions. During the last 6 years considerably more data have been published on this class of compounds. The chapter reviews the disposition and pharmacokinetics and identifies congener and species-specific factors that may have an impact on the dose-related biological responses of these compounds.