Record Display for the EPA National Library Catalog

RECORD NUMBER: 37 OF 330

Main Title Combining Pharmacokinetic and Cancer Bioassay Data.
Author Whittemore., A. S. ;
CORP Author Stanford Univ., CA. Dept. of Family, Community and Preventive Medicine.;National Institutes of Health, Bethesda, MD.;Electric Power Research Inst., Palo Alto, CA.;Alfred P. Sloan Foundation, New York.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher 1986
Year Published 1986
Report Number NIH-PHS-00070 ;NIH-PHS-CA-23214; EPA/600/D-90/047;
Stock Number PB90-246125
Additional Subjects Toxicology ; Carcinogens ; Bioassay ; Exposure ; Humans ; Laboratory animals ; Metabolism ; Reprints ; Pharmacokinetics ; Risk assessment ; Carcinogenicity tests ; Predictive value of tests ; Dose-response relationships ; Species diversity
Holdings
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Status
NTIS  PB90-246125 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 16p
Abstract
Despite formidable sources of uncertainty, risk assessments are needed to avoid the extremes of either banning or allowing all exposures to potentially harmful chemicals. The paper addresses methods for reducing uncertainty in relationships between human exposures and disease, particularly cancer. Attention will focus on possible improvements in the use of animal experiments to predict human cancer risks.