Record Display for the EPA National Library Catalog


Main Title Evoked Potentials: Physiological Methods with Human Applications.
Author Dyer, R. S. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher 1989
Year Published 1989
Report Number EPA/600/D-89/063;
Stock Number PB89-223614
Additional Subjects Evoked potentials ; Nervous system disorders ; Electrophysiologic tests ; Toxicology ; Rats ; Brain stem ; Electroencephalography ; Senses ; Neurotoxins ; Somatosensory cortex ; Visual cortex ; Auditory cortex ; Animal models ; Neurotransmitters
Library Call Number Additional Info Location Last
NTIS  PB89-223614 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 15p
A number of tests and test batteries have been developed and implemented for detecting potential neurotoxicity in humans. In some cases test results may suggest specific dysfunction. While tests in laboratory animals are often used to project the potential for adverse health effects in humans, reverse extrapolation may also be desirable. When changes in physiological measures are indicated in humans, it may be important to pinpoint the nature of the effect and understand its underlying biology. A first step in this process can be taken using animal models with demonstrated homology to the human case. The paper will focus upon 3 physiological methods which have been used in the neurological clinic to evaluate sensory function in humans, and which have also been used in laboratory animals to evaluate toxicant-induced dysfunction.