The manual, in support of the Florida Radon Research Program, contains standard protocols for key measurements where data quality is vital to the program. It contains two sections. The first section, soil measurements, contains field sampling protocols for soil gas permeability and radon concentration, in-situ soil density, soil classification, and penetrometer analysis. Laboratory procedures include soil moisture, radium and radon emanation, particle-size analysis, specific gravity, the proctor method for moisture/density relationships, a laboratory gas permeability test, a radon diffusion coefficient measurement, and two radon flux measurements. The second section, building measurements, includes diagnostic procedures for sub-slab radon, sub-slab communication, and differential pressure measurements followed by building leakage measurements.