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Main Title Letter from (Confidential) to USEPA Submitting Local Lymph Node Assay Skin Sensitization Studies (7) for Chemical Substances and Mixtures (Confidential), with Attachments (6) and dated 08/30/2000 (Sanitized).
CORP Author ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number FYI-OTS-0900-1391S
Stock Number OTS0001391
Additional Subjects Toxicology ; Health effects ; Skin sensitizations ; Acute toxicity ; Lymph nodes ; Mice ; Mammals
Holdings
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Status
NTIS  OTS0001391 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 302p
Abstract
A sample of (confidential) was assessed for its skin sensitisation potential using the mouse Lymph Node Assay. The assay determines the level of T lymphocyte proliferation in the lymph nodes draining the site of chemical application, by measuring the amount of radiolabelled thymidine incorporated into the dividing cells. The test substance was applied as 3%, 10% or 30% w/v preparations in acetone.