Includes bibliographical references and index.

Cutaneous toxicity: introduction / Victor A. Drill -- What is a reaction: factors in the interpretation and reporting of cosmetic data / Paul Lazar -- Practical and theoretical considerations in evaluating dermal safety / Dorothy B. Hood -- Adequately substantiating the safety of topical products / Robert P. Giovacchini -- The skin as a target organ for systemic agents / Jerome L. Shupack -- Cutaneous absorption and systemic toxicity / Donald J. Birmingham -- Factors affecting percutaneous absorption / Frederick D. Malkinson and Louisa Gehlmann -- New procedures for evaluating cutaneous absorption / Jane E. Shaw [and others] -- Metabolism of cutaneously applied surfactants / Robert B. Drotman -- Percutaneous absorption in man and animal: a perspective / Ronald C. Wester and Howard I. Maibach -- The chamber-scarification test for assessing irritancy of topically applied substances / Peter J. Frosch and Albert M. Kligman -- Prediction of skin irritancy and sensitizing potential by testing with animals and man / John F. Griffith and Edwin V. Buehler -- In vitro experimental approaches to detection of sensitizing agents / Albert E. Munson, Beverly A. Barrett, and Joseph F. Borzelleca -- The value and significance of carcinogenic, mutagenic, and teratogenic tests / David J. Brusick -- The chemistry and toxicology of hair dyes / Clyde M. Burnett and John F. Corbett -- Controlling infections: the hospital environment and handwashing / George F. Mallison and Allen C. Steere, Jr. -- The cutaneous absorption and systemic toxicity of antimicrobials: FDA concerns / Mary K. Bruch -- Toxicologic perspectives on chemicals commonly applied to the skin / Howard I. Maibach and Francis N. Marzulli -- Cosmetic legislation: a congressional viewpoint / Thomas F. Eagleton.