||Pharmacological Effects of Carbaryl II. Modification of Serotonin Metabolism in the Rat Brain.
Hassan, A. ;
Santolucito., J. A. ;
||Environmental Protection Agency, Perrine, Fla. Primate and Pesticides Effects Lab.
Laboratory animals ;
Experimental data ;
Physiological effects ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The purpose of the present investigation was to study the effect of a single carbaryl dose on serotonin metabolism in the rat brain. Male albino rats (Holtzman) weighing 150-180 g were used in this study. All animals were housed in groups for several weeks, and fed a standard diet of Purina laboratory chow. Carbaryl was administered orally as a suspension in peanut oil at a single dosage of 60 mg/kg. Control rats received only peanut oil. Animals were killed by decapitation, and the brain was quickly removed and extracted. All determinations were made on whole brain.