Record Display for the EPA National Library Catalog

RECORD NUMBER: 5 OF 9

Main Title On the Question of the Mode of Action of the Bronchosecretolytic Agent, N-Cyclohexyl-N-Methyl-(2-Amino-3, 5-Dibromobenzyl)-Ammonium Chloride.
Author Eigelsreiter, H. ; Mair., M. ;
CORP Author National Institutes of Health, Bethesda, Md. Translation Unit.;Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1974
Report Number NIH-74-05C; EPA-TR-84-74;
Stock Number PB-237 908-T
Additional Subjects Muscle relaxants ; Bronchi ; Secretion ; Drugs ; Respiratory system ; Pharmacology ; West Germany ; Translations ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-237 908-T Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract
Although it appears to be certain that N-Cyclohexyl-N-methyl-(2-amino-3, 5-dibromobenzy)-ammonium chloride (Bisolvon) has an expectoration-promoting effect in animals, and human beings, the mechanism of action has not been thoroughly elucidated. Beside the reduction of viscosity of the bronchial secretion and a considerable increase in the granula of the secretion and of lysosomes in the caliciform cells, there also exists a dispute over an increased absorption from the bronchial tract. In the present examination an experiment was undertaken for the purposes of further clarification of the mechanism of action of Bisolvon.