The Health and Environmental Effects Profile for chlorthalonil was prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste to support listings of hazardous constituents of a wide range of waste streams under Section 3001 of the Resource Conservation and Recovery Act (RCRA). Both published literature and information obtained from Agency program office files were evaluated as the authors pertained to potential human health, aquatic life and environmental effects of hazardous waste constituents. Quantitative estimates have been presented provided sufficient data are available. Chlorthalonil has been evaluated as a carcinogen. The human carcinogen potency factor (q(l)*) for chlorthalonil is .002 (mg/kg bw/day)-1 for oral exposure.

"Prepared by Syracuse Research Corporation under EPA contract no. 68-03-3228." "Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development." "January 1984." "EPA 600-X-84-321." Includes bibliographical references (leaves 21-27).

1. Introduction -- 1.1. Structure and CAS number -- 1.2. Physical and chemical properties -- 1.3. Production data -- 1.4. Use data -- 2. Environmental fate and transport processes -- 3. Exposure -- 4. Pharmacokinetics -- 4.1. Absorption -- 4.2. Distribution -- 4.3. Metabolism -- 4.4. Excretion -- 5. Effects -- 5.1. Carcinogenicity -- 5.2. Mutagenicity -- 5.3. Teratogenicity -- 5.4. Other reproductive effects -- 5.5. Chronic toxicity -- 5.6. Other relevant information -- 6. Aquatic toxicity -- 6.1. Acute -- 6.2. Chronic -- 6.3. Plant effects -- 6.4. Residue -- 6.5. Other relevant information -- 7. Existing guideline and standards -- 7.1 Human -- 7.2. Aquatic -- 8. Risk assessment -- 9. References -- Appendix A: literature searched -- Appendix B: cancer data sheet for derivation of q1* -- Appendix C: cancer data sheet for derivation of q1*