Includes bibliographical references.

Consensus report -- Mutations and altered expression of human cancer genes: what they tell us about causes / T.R. Devereux, J.I. Risinger and J.C. Barrett -- Analysis of somatic mutations of the p53 gene in human cancers: a tool to generate hypotheses about the natural history of cancer / T. Hernandez-Boussard, R. Montesano and P. Hainaut -- Mutations in ras genes in experimental tumours of rodents / R.C. Sills, G.A. Boorman, J.E. Neal, H.L. Hong and T.R. Devereux -- Mutations patterns in non-ras oncogenes and tumour suppressor genes in the experimentally induced tumours / A.O. Perantoni and J.M. Rice -- Genetically altered mouse models for identifying carcinogens / R.W. Tennant, S. Stasiewicz, J. Mennear, J.E. French and J.W. Spalding -- Use of non-mammalian species in bioessays for carcinogenicity / T.E. Bunton -- Chemically induced preneoplastic lesions in rodents as indicators of carinogenic activity / G.M. Williams -- Short-and medium-term carcinogenicity tests: simple initiation-promotion assay systems / H. Tsuda, C.B. Park and M.A. Moore -- Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals / T. Shirai, M. Hirose and N. Ito -- Active cell death (apoptosis) and cellular proliferation as indicators of exposure to carcinogens / R. Schulte-Hermann, W. Bursch, B. Marian and B. Grasl-Kraupp -- DNA adducts in mammalian cells as indicators of exposure to carcinogens / D.E.G. Shuker -- DNA damage and repair in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens / D. McGregor and D. Anderson -- Mutation in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens / A.A. van Zeeland and H. Vrieling -- Induction of mutations in transgenic animal models: BigBlue(TM) and Muta(TM)Mouse / P. Schmezer and C. Eckert -- Chromosomal changes / R.J. Preston -- Use of Syrian hamster embryo and BALB/c 3T3 cell transformation for assessing the carcinogenic potential of chemicals / R.A. LeBoeuf, K.A. Kerckaert, M.J. Aardema and R.J. Isfort -- The results of assays in Drosophila as indicators of exposure to carcinogens / E.W. Vogel, U. Graf, H.J. Frei and M.M.J. Nivard -- Use of test in yeasts and fungi in the detection and evaluation of carcinogens / J.M. Parry -- Identification of carcinogenic substances by means of short-term tests in bacteria / P. Quillardet and D. McGregor -- Short-term tests for defining mutagenic carcinogens / M.D. Waters, H.F. Stack and M.A. Jackson.