Record Display for the EPA National Library Catalog

RECORD NUMBER: 162 OF 2486

Main Title Approach to Environmental Risk Assessment Using Avian Toxicity Tests (Journal Version).
Author Shirazi, M. A. ; Bennett, R. S. ; Lowrie, L. ;
CORP Author Corvallis Environmental Research Lab., OR. ;Northrop Services, Inc., Corvallis, OR.
Publisher c1988
Year Published 1988
Report Number EPA/600/J-88/258;
Stock Number PB89-143747
Additional Subjects Lethal dosage ; Hazardous materials ; Weibull density functions ; Toxicity ; Birds ; Bioassay ; Tables(Data) ; Pesticides ; Statistical distributions ; Mathematical models ; Reprints ; Risk assessment ; Environmental tests ; Dose-response relationships
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NTIS  PB89-143747 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract
Toxicity tests results are often condensed into a single endpoint (LC50) to facilitate their use in environmental management. The single number cannot distinguish between two tests with equal LC50s but dissimilar slopes at LC50 and it cannot describe the response at low and high dose levels. Some chemicals produce a flat response at low dose levels, others produce a steep response. The management of different chemicals requires different strategies and a more comprehensive approach to analysis of test data than use of a single endpoint. An alternative analysis of test data using Weibull survivor function produces information on the overall form of the dose-response curve and enables calculation of toxicity, the slope, and errors at arbitrary protection levels, including the conventional 50% level. (Copyright (c) 1988 Springer-Verlag New York Inc.)