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RECORD NUMBER: 2 OF 3

Main Title Environmental Protection Agency's Methodology for Assessing Risk of Exposure to Nasal Carcinogens.
Author Pepelko, W. E. ;
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher Nov 88
Year Published 1988
Report Number EPA/600/D-88/242;
Stock Number PB89-130496
Additional Subjects Carcinogens ; Respiratory neoplasms ; Nose(Anatomy) ; Respiration ; Inhalation ; Tests ; Laboratory animals ; Risk ; Hazardous materials ; Air pollution ; US EPA
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-130496 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Abstract
The U.S. Environmental Protection Agency has carried out risk assessments on a variety of chemicals that have been shown to induce nasal tumors in animals and/or humans. Human cancer potency estimates, however, were not always based on the induction of nasal tumors. For those that were, studies employing the inhalation route of exposure were used, with one exception. Extrapolation from the inhalation to the oral route has not been attempted for nasal carcinogens. A variety of uncertainties in assessing potency of nasal carcinogens is being addressed.