This document provides EPAs guidance for preparing the 2006 Integrated Report. The Integrated Report is intended to satisfy the listing requirements of sections 305(b) and 314 of the Clean Water Act (CWA). This guidance document discusses existing requirements of the CWA and EPAs implementing regulations. Those statutory and regulatory provisions contain legally binding requirements. This document describes those requirements; it does not substitute for them. The recommendations in this document are not binding; indeed, there may be other approaches that would be appropriate in particular circumstances. When EPA makes a decision on a states section 303(d) list, it will make each decision on a case-by-case basis and will be guided by the applicable requirements of the CWA and implementing regulations, taking into account comments and information presented at that time by interested persons regarding the appropriateness of applying these recommendations to the particular situation.