| Main Title |
Battery of Acute Toxicity Tests with Cover Letter. |
| CORP Author |
Food and Drug Research Labs., Inc., Conshohocken, PA. ;Rohm and Haas Co., Philadelphia, PA. Research Labs.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
23 Feb 1983 |
| Year Published |
1983 |
| Report Number |
878213508; |
| Stock Number |
OTS-0205842 |
| Additional Subjects |
Toxicity ;
Testing ;
Dermal absorption ;
Oral dosage ;
Skin(Anatomy) ;
Eye irritation ;
Mortality ;
Inhalation ;
Respiratory distress ;
Rats ;
Rabbits ;
Laboratory animals ;
Exposure ;
4-(1,1,3,3-tetramethyl butyl)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0205842 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
40p |
| Abstract |
Six New Zealand albino rabbits, 2 to 3 kg, were closely clipped over the back and sides with an Oster electric clipper. A 0.5 gram portion of the test material was introduced under a 1.5 inch, 12-ply gauze patch placed directly over the test site and held in place with Dermicel tape. The rabbits were wrapped with rubber damming for an exposure period of 4 hours. Slight erythema was observed in 4 animals after 4 hours. All signs of irritation had disappeared in 24 hours. Rohm and Haas Company sample '6-8815, Octylphenol,' when applied to the skin of New Zealand albino rabbits in the quantity of 0.5 ml produced no signs of corrosivity. |
