| Main Title |
NTP technical report on the toxicology and carcinogenesis studies of cumene (CAS no. 98-82-8) in F344/N rats and B6C3F1 mice : (inhalation studies) / |
| Publisher |
National Toxicology Program, U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, |
| Year Published |
2009 |
| OCLC Number |
325002005 |
| Subjects |
Benzene Derivatives--toxicity--Technical Report ;
Mice, Transgenic--Technical Report ;
Rats, Inbred F344--Technical Report ;
Toxicity Tests--Technical Report ;
Toxicology testing ;
Carcinogenicity testing
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| ELBM |
RC268.5.C39 2009 no.542 |
|
AWBERC Library/Cincinnati,OH |
08/12/2013 |
|
| Collation |
200 p. : ill. ; 28 cm. |
| Notes |
"February 2009." Includes bibliographical references. |
| Contents Notes |
Abstract -- Explanation of levels of evidence of carcinogenic activity -- Technical reports review subcommittee -- Introduction -- Materials and methods -- Results -- Discussions and conclusions -- References -- Summary of lesions in male rats in the 2-year inhalation study of cumene -- Summary of lesions in female rats in the 2-year inhalation study of cumene -- Summary of lesions in male mice in the 2-year inhalation study of cumene -- Summary of lesions in female mice in the 2-year inhalation study of cumene -- Genetic toxicology -- Clinical pathology results -- Organ weights and organ-weight-to-body-weight ratios -- Reproductive tissue evaluations and estrous cycle characterization -- Chemical characterization and generation of chamber concentrations -- Ingredients, nutrient composition, and contaminant levels in NTP-2000 rat and mous ration -- Sentinel animal program -- Characterization of K-ras and p53 mutations in lung neoplasms of mice in the 2-year inhalation study of cumene |
