Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Radioimmunoassay of metallothionein /
Author Friedberg, Felix.
Other Authors
Author Title of a Work
Hall, Larry L.
CORP Author Howard Univ., Washington, D.C. Dept. of Biochemistry.;Health Effects Research Lab., Research Triangle Park, N.C. Environmental Toxicology Div.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1978
Report Number PB277048; EPA-600/1-78-010; EPA-R-803201
Stock Number PB-277 048
OCLC Number 52465207
Subjects Metallothionein. ; Radioimmunoassay.
Additional Subjects Proteins ; Amino acids ; Metals ; Cadmium ; Zinc ; Copper ; Transport properties ; Chemical composition ; Assaying ; Radioimmunoassay ; Metallothionein proteins
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-78-010 Headquarters Library/Washington,DC 04/28/2014
EJBD  EPA 600-1-78-010 c.1 Headquarters Library/Washington,DC 06/09/2014
EKBD  EPA-600/1-78-010 Research Triangle Park Library/RTP, NC 06/27/2003
ELBD RPS EPA 600-1-78-010 repository copy AWBERC Library/Cincinnati,OH 07/07/2016
NTIS  PB-277 048 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation iii, 12 pages ; 28 cm.
The goal of this project was to develop a radioimmunoassay for metallothionein. Since this protein is involved with the transport of cadmium in biological systems and may in fact protect against cadmium poisoning, the ability to monitor the levels in the human population is of the utmost importance to evaluation of the hazards of environmental cadmium exposure. While researchers do not agree whether copper thioneins and zinc thioneins of rats are identical, this study found in preliminary analysis that zinc thionein appears to have a composition similar to that of copper chelatins. It is recommended that development of a radioimmunoassay should not be attempted until the putative metallothioneing is clearly characterized. There are too many kinds of metallothionein induced by the injection of different metals according to the reports in the literature. They must be properly identified first.
Project Officer: Larry L. Hall. "January 1978." "EPA-600/1-78-010." PB 277 048--NTIS. Includes bibliographical references.