Significant changes have been made in the long range goals and objectives of the Colorado River Basin Project on Water Quality Control. The scope has been changed from the development of a comprehensive program to investigation of the critical and pressing interstate pollution problems which may exist now or in the future in the Basin. Salinity continues to be the major pollution problem. A surveillance program with respect to radiological pollution is being carried forward. These programs are detailed in activities reports. A pesticide investigation has been undertaken to gather information on existing concentrations and loadings of selected pesticides in the lower main stream. The significance of the findings are to be assessed with respect to municipal water use and effects on aquatic life. A limited number of herbicide analyses is included in the investigation. Future plans and organization are set forth.