Record Display for the EPA National Library Catalog


Main Title Thyroid Cancer Risk from Exposure to Ionizing Radiation: A Case Study in the Comparative Potency Model.
Author Laird., N. M. ;
CORP Author Harvard School of Public Health, Boston, MA.;Health Effects Research Lab., Research Triangle Park, NC.;Department of Energy, Washington, DC.
Publisher c1987
Year Published 1987
Report Number DE-AC04-76DP00789; EPA/600/J-87/519;
Stock Number PB90-232232
Additional Subjects Thyroid neoplasms ; Iodine 131 ; Epidemiology ; Exposure ; Ionizing radiation ; Aging(Biology) ; Reprints ; Risk assessment ; Radiation-induced neoplasms ; Radiation dose-response relationships
Library Call Number Additional Info Location Last
NTIS  PB90-232232 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Considerable controversy exists about the relative risk of thyroid cancer following exposure to external radiation compared to the risk after exposure to internally deposited 131I. The human epidemiological data are equivocal, and studies are not directly comparable owing to differing ages at exposure, dose ranges, and periods of follow-up. Limited experimental data at low dose ranges support the hypothesis of equal potency in animals. The report utilizes a relative potency model to reconcile data from different sources, and to provide an estimate of thyroid cancer risk following human exposure to 131I. Data from epidemiological studies of external radiation and 131I exposure in humans and data from an experimental animal study is utilized. The analysis shows that the data provide no compelling evidence to suggest that the risks accompanying external radiation or 131I exposure are different. (Copyright (c) 1987 Society for Risk Analysis.)