Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Report of an Animal Experiment to Analyze Silica Gel Dust by Intratracheal and in Traperitoneal Injections in a Rat with Cover Letter dated 07/24/80.
CORP Author MCB Manufacturing Chemists, Inc., Cincinnati, OH.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 30 Jul 1980
Year Published 1980
Report Number 8HEQ-0780-0354;
Stock Number OTS-0204857
Additional Subjects Silica gel ; Rats ; Trachea ; Dust ; Quartz ; Body weight ; Toxicology ; Pathology ; Dosage ; Silicosis ; Laboratory animals ; Lymph nodes ; Heart ; Liver ; Spleen ; Salts ; Granuloma ; Intramuscular injections ;
Library Call Number Additional Info Location Last
NTIS  OTS-0204857 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/09/2008
Collation 40p
The reaction and behavior of rats when injected with silica gel dust are being tested, as opposed to the reaction and behavior of a pure quartz dust application. For the experiment we used female Wistar rats weighing 250g. The animals were nourished with Altronium-R and water ad libitum. The dust originated from a fine dust sample from E. Merck, Darmstadt. The quartz was Doerentruper Nr. 12, sedimented to less than 3 micrograms. Both were suspended in a sterile 0.9 salt solution. The intratrachea injection contained a dust dose of 30mg/animal in 0.5ml salt solution-the intraperitoneum injections 50mg/animal in 1.0ml salt solution.