Includes bibliographical references.

Introduction and overview -- Imperative : managing rapidly increasing complexity -- Imperative : achieving greater value in health care -- Imperative : capturing opportunities from technology, industry, and policy -- A continuously learning health care system -- Generating and applying knowledge in real time -- Engaging patients, families, and communities -- Achieving and rewarding high-value care -- Creating a new culture of care -- Actions for continuous learning, best care, and lower costs.