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Main Title Synthetic studies towards bioactive heterocycles : Pyrrole-2-carbaldehydes and N-Heterocyclic amino acids /
Author Wood, James,
Year Published 2018
OCLC Number 1066227278
Subjects Heterocyclic compounds--Synthesis ; Bioactive compounds--Synthesis ; Amino acids--Synthesis ; Pyrroles--Synthesis
Internet Access
Description Access URL
http://hdl.handle.net/2292/37667
Holdings
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Status
ELBM  QD341.E7W66 2018 AWBERC Library/Cincinnati,OH 02/26/2020
Collation xii, 437 pages : illustrations (some colour) ; 30 cm
Notes
"A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy, School of Chemical Sciences, University of Auckland, March 2018." Includes bibliographical references.
Contents Notes
This thesis is comprised of two parts and describes synthetic efforts towards bioactive N-heterocyclic scaffolds. Part One describes synthetic studies towards pyrrole-2-carbaldehydes using a Maillard-type reaction ... Part Two describes synthetic studies towards N-heterocyclic amino acid isosteres of L-alloenduracididine (430) ; a component of the recently isolated antibiotic teixobactin (423) which exhibits potent bactericidal activity without detectable antimicrobial resistance.