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Main Title Comparison of Both Neoplastic and Non-Neoplastic Disorders in Winter Flounder (Pseudopleuronectes americanus) from Eight Areas in New England.
Author Gardner, G. R. ; Pruell, R. J. ; Folmar., L. C. ;
CORP Author Environmental Research Lab., Narragansett, RI.
Publisher c1990
Year Published 1990
Report Number ERNL-1034 ;EPA/600/J-90/074;
Stock Number PB90-245531
Additional Subjects Fish diseases ; Liver neoplasms ; Aromatic polycyclic hydrocarbons ; Blood proteins ; Pathology ; Copper ; Cadmium ; Lead(Metal) ; Reprints ; Flounder ; New England ; Pseudopleuronectes americanus ; Polychlorobiphenyl compounds
Library Call Number Additional Info Location Last
NTIS  PB90-245531 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Distribution patterns of liver disease observed in winter flounder indigenous to the northeastern USA indicated that hepatocytic neoplasms were absent in populations from uncontaminated offshore areas and endemic in populations from moderately to highly contaminated inshore areas. Liver neoplasms in winter flounder collected from eight different locations ranged from 0% in animals collected offshore from Cape Cod to 32% in the nearshore area of New Bedford, MA. Similarly, an array of other hepatic lesions ranged from 9% in Martha's Vineyard to 79% in Boston Harbor. Proliferate lesions in endocrine, exocrine, respiratory, sensory, excretory and digestive organs and alteration of plasma protein were also characteristic of winter flounder populations residing in the nearshore environment. The concentrations of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), other organic compounds and trace metals associated with marine sediment were elevated in urban embayments as compared with offshore locations. (Copyright (c) 1990 Elsevier Science Publishers Ltd., England.)