Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Radiofrequency Radiation-Induced Calcium-Ion-Efflux Enhancement from Human and Other Neuroblastoma Cells in Culture: (Final Technical Report).
Author Dutta, S. K. ; Ghosh, B. ; Blackman, C. F. ;
CORP Author Howard Univ., Washington, DC.;Environmental Protection Agency, Research Triangle Park, NC. Health Effects Research Lab.;Department of Energy, Washington, DC.
Year Published 1988
Report Number DOE/RL/11374-T1; AI06-87RL11374;
Stock Number DE88011609
Additional Subjects Cell Cultures ; Nerve Cells ; Radiowave Radiation ; Biological Radiation Effects ; Calcium 45 ; Dose Rates ; Progress Report ; Tracer Techniques ; ERDA/560120 ; ERDA/550501 ; ERDA/560400 ; Neuroblastoma ; Electromagnetic radiation ; Calcium ; Biological transport
Library Call Number Additional Info Location Last
NTIS  DE88011609 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 12/29/1988
Collation 14p
In order to test the generality of radiofrequency-radiation-induced change in alternation of sup 45 Ca/sup 2/plus// efflux from avian and feline brain tissues, human neuroblastoma cells were exposed to electromagnetic radiation at 147 MHz, amplitude modulated (AM) at 16 Hz, at specific absorption rates (SAR) of 0.1, 0.05, 0.01, 0.005, 0.001, and 0.0005 Wkg. Significant sup 45 Ca/sup 2/plus// efflux was obtained at SAR values of 0.05 and 0.005 Wkg. Enchanced efflux at 0.05 Wkg peaked at the 13-to-16 Hz and at the 57.5-to-60 Hz modulation ranges. A Chinese hamster-mouse hybrid neuroblastoma was also shown to exhibit enchanced radiation-induced sup 45 Ca/sup 2/plus// efflux at an SAR of 0.05 Wkg, using 147 MHz, AM at 16 hz. These results confirm that amplitude-modulated radiofrequency radiation can induce response in cells of nervous tissue origin from widely different animal species including humans. The results are also consistent with reports of similar findings in avian and feline brain tissue reported by others and indicate the general nature of the phenomenon.