| Main Title |
Initial Submission: Acute Oral Toxicity and Skin Absorption and Irritation of 3-Chloropropionitrile in Rats and Guinea Pigs with Cover Letter dated 08/26/1992. |
| CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
EPA-OTS-88-920009469 |
| Stock Number |
OTS0571125 |
| Additional Subjects |
Toxicology ;
Health effects ;
3-Chloroproprionitrile ;
Acute toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Primary dermal irritation ;
Guinea pigs ;
Dermal ;
CAS No 542-76-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571125 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
The report pertains to 3-chloropropanenitrile (synonym: 3-chloropropionitrile) (CAS No. 542-76-7) and is being submitted because of lethality with central nervous system (CNS) signs observed in an acute oral toxicity study in rats. The oral LD50 is 10-50 mg/kg in rats. The material is also a slight skin irritant. The dermal LD50 is 0.05-0.1 cc/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement). |
