Record Display for the EPA National Library Catalog
RECORD NUMBER: 78 OF 151| Main Title | Initial Submission: Preliminary Study of the Effect of Toluene on Pregnancy of the Rat (Inhalation Exposure). Final Report with Cover Letter dated 07/22/92. | |||||||||||
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| CORP Author | Huntingdon Research Centre PLC (England). ;American Petroleum Inst., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
| Publisher | 24 Jun 1992 | |||||||||||
| Year Published | 1992 | |||||||||||
| Report Number | FYI-OTS-0792-0857; | |||||||||||
| Stock Number | OTS-0000857 | |||||||||||
| Additional Subjects | Toluene ; Toxicity testing ; Pregnancy ; Rats ; Inhalation tests ; In utero ; Narcosis ; Solvents ; Fetuses ; Dosage ; Maternal toxicity ; American Petroduleum Institute | |||||||||||
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| Collation | 101p | |||||||||||
| Abstract | In this assessment of the effect of Toluene, a solvent, on the pregnancy and in utero development of the rat, dosages of 0, 500, 1000, 2000, 3500 and 5000 ppm were administered by inhalation for a period of 6 hours a day from Day 6 to 15 of pregnancy inclusive. On Day 20, surviving females were sacrificed, subjected to post mortem examination with liver weights being recorded. Litter values were determined and fetuses were examined externally. |