Record Display for the EPA National Library CatalogRECORD NUMBER: 2 OF 4
|Main Title||Evaluation of the potential carcinogenicity of polychlorinated biphenyls (1336-36-7) : including specific aroclors /|
|CORP Author||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA/600/8-91/174; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-162|
|Additional Subjects||Polychlorinated biphenyls ; Aroclors ; Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS: 1336-36-3 ; CAS: 11097-69-1 ; CAS: 11096-82-5 ; CAS: 12672-29-6 ; CAS: 53469-21-9 ; CAS: 11141-16-5 ; CAS: 11104-28-2 ; CAS: 12674-11-2|
|Collation||36 pages ; 28 cm|
Polychlorinated biphenyls (PCBs) are probable human carcinogens, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is suggestive but 'Inadequate'. The potency factor (F) for PCBs, including each of the specific Aroclors, is estimated to be 50.47 (mg/kg/day)-1 based on data from a study using Aroclor 1260, placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, PCBs, including each of the specific Aroclors, are assigned a 'MEDIUM' hazard ranking.
Cover title. "June 1988." Includes bibliographical references. Microfiche.