Record Display for the EPA National Library Catalog

RECORD NUMBER: 3709 OF 4579

OLS Field Name OLS Field Data
Main Title Selection of adduct-forming chemicals for human monitoring studies /
CORP Author Environmental Monitoring Systems Lab., Las Vegas, NV.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Monitoring Systems Laboratory ; Distributed by the National Technical Information Service,
Year Published 1991
Report Number EPA 600-8-91-045; 68-C0-0049
Stock Number PB92-132877
OCLC Number 37399457
Subjects Chemicals--Testing. ; Toxicity testing.
Additional Subjects DNA adducts ; Toxicity ; Environmental pollutants ; Carcinogens ; Exposure ; Biological markers ; Tables(Data) ; Environmental exposure pathways
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100CWTO.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD ARCHIVE EPA 600-8-91-045 Headquarters Library/Washington,DC 04/17/2018
NTIS  PB92-132877 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation vii, 30, [44] pages ; 28 cm
Abstract
The U.S. EPA, through its Environmental Monitoring Systems Laboratory-Las Vegas (EMSL-LV) and its Health Effects Research Laboratory-Research Triangle Park (HERL-RTP) has been exploring the feasibility of using biological markers to monitor exposure to environmental chemicals. The participants began by compiling a list of chemicals of known or suspected health hazards and for which the potential for human exposure exists. The chemicals on the master list were then systematically evaluated for: (1) the potential for adduct-formation in vivo, (2) the availability of supportive adduct research data, (3) the identifiability of exposed population(s), and (4) the level of genetic activity. After considering all the relevant data, the participants selected and prioritized for further study a small group of chemicals considered to have the greatest potential for use in pilot, adduct-based, biological monitoring studies in human populations.
Notes
"EPA 600-8-91-045"--Cover. "May, 1991." "July 1991"--Cover. Contract 68-C0-0049 to Lockheed Engineering and Sciences Company.