| Main Title |
Analysis of the Distribution and Dose Response of Chromosome Aberrations in Human Lymphocytes after In vitro Exposure to (137) Cesium Gamma Radiation. |
| Author |
Doggett, N. A. ;
McKenzie, W. H. ;
|
| CORP Author |
North Carolina State Univ. at Raleigh.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA-R-805739; EPA/600/J-83/287; |
| Stock Number |
PB85-177863 |
| Additional Subjects |
In vitro analysis ;
Cesium 137 ;
Chromosomes ;
Gamma rays ;
Lymphocytes ;
Environmental surveys ;
Dosage ;
Exposure ;
Dosimetry ;
Comparison ;
Humans ;
Poisson density functions ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-177863 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
21p |
| Abstract |
The chromosome aberration yield for human lymphocytes exposed in vitro to various doses of (137) Cesium has been studied. Dicentric, total acentric, and excess acentric data were seen to follow a Poisson distribution. Calculated total hits demonstrated over-dispersion which could possibly be accounted for by a greater occurrence of single-hit phenomena being repaired than two-hit exchange processes. The resulting distribution generally contained an under-representation of cells with odd numbers of hits and an over-representation of zero- and even-hit classes as compared with Poisson predicted values. A possible use of scoring 'normal' cells for purposes of biological dosimetry is presented. |
