Record Display for the EPA National Library Catalog


Main Title Adenocarcinoma of the Retinal Pigment Epithelium in the Guppy 'Poecilia reticulata' Peters.
Author Fournie, J. W. ; Hawkins, W. E. ; Walker, W. W. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL. ;Gulf Coast Research Lab., Ocean Springs, MS.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-92/387 ;CONTRIB-738;
Stock Number PB93-121192
Additional Subjects Adenocarcinoma ; Pigment epithelium of eye ; Eye neoplasms ; Pathology ; Cells(Biology) ; Reprints ; Poecilia reticulata
Library Call Number Additional Info Location Last
NTIS  PB93-121192 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
A single case of adenocarcinoma of the retinal pigment epithelium occurred in a guppy, Poecilia reticulata, Peters. This is the first such tumour reported from fishes. The left eye of the affected fish was severely exophthalmic because of a large intraocular tumour mass. The tumour, which displaced normal retina anteriorly, consisted mainly of melanin-containing epithelial cells. Neoplastic cells were bilayered and arranged in a tubular pattern. The tumour was confined to the orbit. Although the specimen was from a group exposed to a mixture of halogenated organic compounds, the lesion was not considered to have been chemically induced because of its rare occurrence within the group as a whole. (Copyright (c) 1992 Academic Press Limited.)