The purpose of this study was to gather definitive scientific results about the formation and transport of ozone and fine aerosols. Such information would greatly aid in designing a rational control strategy for secondary pollution, based on the control of precursor emissions. The co-occurrence of elevated levels of ozone and light scattering aerosols, particularly sulfates, has been shown in regional scale episodes, in large urban plumes, in aging power plant plumes and in smog chambers. In this report, MISTT data from the Labadie power plant plume is re-examined to investigate the ozone-aerosol link more closely and to identify the ambient conditions most conducive to the generation of the smog-haze pollution. A variety of air quality as well as meteorological and navigational parameters were continuously measured from aircraft. Based on theoretical and empirical grounds, findings show a close link between the formation of ozone and aerosols in power plant plumes. The conditions of the background air mass into which the plume is emitted and plume background interactions were found significant in the co-generation of ozone and aerosols during long range transport of power plant plumes. Ozone formation was found to be a significant factor. Total nitrate formation may well exceed aerosol sulfate formation during the first several hours of plume transport. This subject deserves more attention in future research.