| Main Title |
Effects of Segregation and Selection on Instability of Plasmid pACYC184 in 'Escherichia coli'B. |
| Author |
Lenski, R. E. ;
Bouma, J. E. ;
|
| CORP Author |
California Univ., Irvine. Dept. of Ecology and Evolutionary Biology.;Environmental Research Lab., Gulf Breeze, FL. |
| Year Published |
1987 |
| Report Number |
EPA-R-813401; EPA/600/J-87/311; |
| Stock Number |
PB88-196241 |
| Additional Subjects |
Tolerances(Physiology) ;
Bacteria ;
Cell division ;
Antibiotics ;
Escherchi coli ;
Mathematical models ;
Selection ;
Deoxyribonucleic acids ;
Populations ;
Dynamics ;
Plasmids ;
Hosts
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-196241 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
The authors use a mathematical model to analyze the dynamics of loss of nonconjugative pACYC184 from populations of Escherichia coli B in glucose-limited continuous culture. The model incorporates both plasmid segregation and selection against plasmid carriage. It is concluded that there is intense selection against plasmid carriage (s = 0.3 per culture generation), which amplifies the frequency of segregants arising de novo. (Copyright (c) 1987, American Society for Microbiology.) |
