Record Display for the EPA National Library CatalogRECORD NUMBER: 2 OF 3
|Main Title||Effect of Chronic Exposure to EPN and to Guthion on the Critical Swimming Speed and Brain Acetylcholinesterase Activity of 'Cyprinodon variegatus'.|
|Author||Cripe, G. M. ; Goodman, L. R. ; Hansen, D. J. ;|
|CORP Author||Environmental Research Lab., Gulf Breeze, FL.|
|Additional Subjects||Pesticides ; Minnows ; Toxicity ; Water pollution ; Survival ; Tests ; Pesticides ; Phosphorus organic compounds ; Swimming ; Acetylcholinesterase ; Life cycles ; Growth ; Reproduction(Biology) ; Bioassay ; Reprints ; Cyprinodon variegatus ; Sheepshead minnows ; EPN insecticide ; Guthion ; Phosphonothioic acid/(ethyl-ester)-(nitrophenyl-ester)-phenyl ; Phosphosphorodiathioic acid/(dimethyl)-(oxobenzotriaziryl)methyl|
Swimming performance of the Sheepshead minnow, Cyprinodon variegatus, was measured in a stamina tunnel at the end of life-cycle toxicity tests with the organophosphate pesticides, EPN and Guthion. Swimming stamina was affected by 2.2 micrograms EPN/l but not by 0.88 micrograms EPN/l; these concentrations are about one half of those that significantly affect survival, growth or reproduction. Fish brain acetylcholinesterase (AChE) activity, assayed by the pH-Stat method, was inhibited 72% by 0.88 micrograms EPN/l and 83% by 2.2 micrograms EPN/l. Swimming performance was not affected by Guthion concentrations up to 0.5 micrograms/l; this concentration reduced survival and inhibited AChE 78%.