Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title In vitro Studies to Evaluate Glycol Ethers as Substrates for Alcohol Dehydrogenase (Sanitized).
CORP Author Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001231S
Stock Number OTS0520741
Additional Subjects Toxicology ; Health effects ; 1-methoxy-2-propanol (107-98-2) ; Pharmaco Kinetics ; Mammals ; Other Mammals ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 107-98-2 ; CAS No 109-86-4 ; CAS No 110-80-5 ; CAS No 111-76-2 ; CAS No 111-77-3 ; CAS No 111-90-0 ; CAS No 112-34-5 ; CAS No 34590-94-8
Library Call Number Additional Info Location Last
NTIS  OTS0520741 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/10/2010
Collation 13p
Metabolism of Dowanol EB (ethylene glycol mono-n-butyl ether) was evaluated in vitro with an equine liver alcohol dehydrogenase assay obtained from the Sigma Chemical Company. The Vmax, Km, and Vmax/Km were 4.06, 1.18X10E-3, and 3.50, respectively. The authors concluded that alcohol dehydrogenase has a high affinity for the test compound, indicating that the test compound is probably metabolized to a significant extent by this enzyme in vivo.